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First exhibited in 1988, Hirst’s Spot works, otherwise known as the Pharmaceutical Paintings, have become one of the most pervasive images in contemporary art. The works were initially conceived as a scientific approach to painting, much like drug companies’ scientific approach to life, and Hirst has sought to depict the innumerable unique arrangements made possible by altering the color, size, and placement of the dots. With works like this, Hirst seamlessly blends high and low culture, adding in his characteristically irreverent humor.